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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13L All Species: 8.18
Human Site: T1541 Identified Species: 15
UniProt: Q71F56 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q71F56 NP_056150.1 2210 242602 T1541 A A A Q G Q A T P G N A G P L
Chimpanzee Pan troglodytes XP_001138050 2188 240763 T1519 N A N T P S A T L A S A V S S
Rhesus Macaque Macaca mulatta XP_001112106 2210 242628 T1541 A A A Q G Q A T P G N A G P L
Dog Lupus familis XP_534693 2280 250152 P1611 A A P G Q A T P G N A G P L A
Cat Felis silvestris
Mouse Mus musculus Q6JPI3 2207 241740 Q1538 P P A E A Q G Q A T P G N A G
Rat Rattus norvegicus NP_001101807 1374 149708 G729 G S G A P P A G S A F N P T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 T1501 S N S G N S N T P S S T P A T
Chicken Gallus gallus XP_415317 2195 241321 V1527 I P G N T G P V P S N S T C L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 G1448 L A S Q S L D G S L L T Q R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 E1955 D D W L R T L E H A A L A E Q
Honey Bee Apis mellifera XP_393643 1982 216109 D1337 R S L L D S G D S Q S N K Q Q
Nematode Worm Caenorhab. elegans Q93442 2862 325119 K2134 F D E Q S D R K E P L E E N D
Sea Urchin Strong. purpuratus XP_001203054 1127 123639 S482 F R T S R H H S S S S G A S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.7 99.2 93.3 N.A. 92.4 57.7 N.A. 53.5 86.4 N.A. 50.2 N.A. 24.8 33.9 21.2 25.6
Protein Similarity: 100 69.3 99.6 94.7 N.A. 95.7 59.9 N.A. 69.7 92.5 N.A. 66.4 N.A. 41.5 50.5 38.5 35.1
P-Site Identity: 100 26.6 100 13.3 N.A. 13.3 6.6 N.A. 13.3 20 N.A. 13.3 N.A. 0 0 6.6 0
P-Site Similarity: 100 33.3 100 13.3 N.A. 20 13.3 N.A. 33.3 26.6 N.A. 20 N.A. 0 13.3 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 39 24 8 8 8 31 0 8 24 16 24 16 16 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 16 0 0 8 8 8 8 0 0 0 0 0 0 8 % D
% Glu: 0 0 8 8 0 0 0 8 8 0 0 8 8 8 0 % E
% Phe: 16 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 16 16 16 8 16 16 8 16 0 24 16 0 8 % G
% His: 0 0 0 0 0 8 8 0 8 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % K
% Leu: 8 0 8 16 0 8 8 0 8 8 16 8 0 8 24 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 8 8 8 0 8 0 0 8 24 16 8 8 8 % N
% Pro: 8 16 8 0 16 8 8 8 31 8 8 0 24 16 0 % P
% Gln: 0 0 0 31 8 24 0 8 0 8 0 0 8 8 16 % Q
% Arg: 8 8 0 0 16 0 8 0 0 0 0 0 0 8 0 % R
% Ser: 8 16 16 8 16 24 0 8 31 24 31 8 0 16 24 % S
% Thr: 0 0 8 8 8 8 8 31 0 8 0 16 8 8 8 % T
% Val: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _